Alzheimer's Disease Research

Alzheimer's disease is characterized pathologically by senile plaques and neurofibrillary tangles in postmortem brains and accounts for the largest proportion of the causes of dementia. Although the molecular mechanism of the onset of Alzheimer's disease has not yet been elucidated, an amyloid cascade hypothesis has been proposed in which amyloid-β (Aβ) gradually accumulates in the brain over several decades before the onset of the disease, abnormally phosphorylated tau protein and the like causes neurofibrillary tangles, and finally neuronopathy occurs and causes symptoms. Fujifilm Wako offers a line-up of reagents that can detect and measure important factors in Alzheimer's disease, including high-performance anti amyloid β antibodies and ELISA kits using these antibodies, as well as Aβ oligomers, tau protein, and phosphorylated tau protein.