StemSure® Serum Replacement is a serum replacement for ES/iPS cell culture. Since serum contains factors that induce differentiation of cells, serum replacements are commonly used when culturing ES/iPS cells to maintain their undifferentiated states. ES/ iPS cells can thus be cultured safely using this product.
The product is safe to handle as it is not categorized as a poisonous substance. Murine ES cells cultured in medium containing StemSure Serum Replacement have been used to create chimera mice and to achieve germline transmission.