Universal Linker "PT Linker Support"

The Phenanthrene-type Linker (PT Linker) is a universal linker for oligonucleotide synthesis. This linker consists of a bicyclic 1,2-diol structure containing a phenanthrene moiety and a succinyl unit that connects the solid support to the phenanthrene via an amide bond. Its high lipophilicity and UV-detectable phenanthrene scaffold facilitate easy separation of the targeted oligonucleotide from linker-derived impurities. 1)